OPTIMAL DOSING AND TIMING OF HIGH-DOSE CORTICOSTEROID THERAPY IN HOSPITALIZED PATIENTS WITH COVID-19: STUDY PROTOCOL FOR A RETROSPECTIVE OBSERVATIONAL MULTICENTER STUDY (SELECT)

BackgroundIn hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely.Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails.In critically ill patients, high-dose corticosteroids are often administered as salvag

Abstract Larvae of holometabolic insects evolved different crawling strategies depending on the presence or absence of larval legs or life POWER CLEANER STYLE REMOVER style.A rather unusual mode of locomotion has independently evolved in legless larvae of several dipteran species.Maggots of the Mediterranean fruit fly Ceratitis capitata developed a

Big geospatial raster data pose a grand challenge to data management technologies for effective big data query and processing.To address these challenges, various big halter data container solutions have been developed or enhanced to facilitate data storage, retrieval, and analysis.Data containers were also developed or enhanced to handle geospatia

Ultrasonic orbital microforming—UOM—uses the broadly understood idea of orbital forging but uses very different laws of physics.The only shaping force in this process is the inertia force resulting from the acceleration in the rotary motion of the workpiece.Micro specimen blanked from cold rolled aluminum sheet metal was used in the app